Look at a simplified scenario with one neuron listening to two others. One of these two neurons might become overactive and send too many signals to the neuron that’s listening. When ever that happens, the neuron that’s listening will make endocannabinoids specifically where really linked to the overactive neuron. Those endocannabinoids will travel returning to the “loud” neuron where they combine to CB1 receptors, sending a signal that advices it to quiet down. This brings things back again to the Goldilocks sector, maintaining homeostasis. buy CBD oil UK
As the example above illustrates, endocannabinoids travel backwards, which is why they’re known as retrograde signals. Most of the time, information stream between neurons is purely in a single course, from “sender” neurons that release neurotransmitter signals to “receiver” neurons that hear to those signals. Endocannabinoids allow receiver neurons to manage how much type they’re getting, and they do this by mailing retrograde signals (endocannabinoids) again to overactive sender neurons.
But the brain basically the sole organ that needs to maintain homeostasis. Every other system of the body, from the digestive to immune system, needs to carefully control how its cells are functioning. Proper regulation is crucial for ensuring endurance.